TAMSO-H® Capsules (ER)

TAMSO-H® Capsules (ER)
Generic Name:
Tamsulosin Hydrochloride
Therapeutic Group:
Urological Agents
Drug Category:
Selective Alpha-1 Adrenergic Receptor Blocker
Content / Composition:
Each prolonged-release capsule contains:
* Tamsulosin Hydrochloride …… 0.4 mg
Indications:
Indicated for the management of:
* Benign Prostatic Hyperplasia (BPH)
* Lower urinary tract symptoms (LUTS) associated with BPH such as:
– Difficulty in urination
– Weak urine flow
– Incomplete bladder emptying
– Nocturia (frequent urination at night)
Dosage:
As directed by the physician.
Typical dosing:
* 0.4 mg once daily after the same meal each day
* If needed, may be increased to 0.8 mg daily (under medical supervision)
Contraindications:
* Hypersensitivity to tamsulosin or any component of the formulation
* History of orthostatic hypotension
* Severe hepatic impairment
Administration:
For oral use.
* Take after meals (preferably after breakfast)
* Swallow capsule whole (do not crush or chew)
* Take at the same time each day
Interaction:
Use caution with:
* Other alpha-blockers (↑ risk of hypotension)
* Antihypertensive drugs
* Strong CYP3A4 inhibitors (e.g., ketoconazole)
* CYP2D6 inhibitors
* PDE-5 inhibitors (e.g., sildenafil) – risk of hypotension
Compatibility:
Can be used with standard BPH therapies.
Combination with 5-alpha reductase inhibitors (e.g., finasteride) may enhance therapeutic effect.
Stability / Storage:
Store below 25°C.
Protect from moisture and light.
Keep out of reach of children.
Precautions:
* Monitor blood pressure (risk of dizziness or fainting)
* Use caution in elderly patients
* May cause intraoperative floppy iris syndrome (IFIS) during cataract surgery
* Not indicated for use in women or children
* Caution in renal impairment
Side Effects:
Common:
* Dizziness
* Headache
* Abnormal ejaculation
Less common:
* Orthostatic hypotension
* Palpitations
* Nasal congestion
Rare but serious:
* Syncope (fainting)
* Severe allergic reactions
* Priapism (very rare)
Website Note (Professional):
Tamsulosin is a highly selective alpha-1 blocker designed to improve urinary flow and reduce symptoms of BPH with minimal impact on blood pressure, offering effective and well-tolerated long-term management.