SYGFOL® Softgels
Generic Name:
L-Methylfolate (5-Methyltetrahydrofolate)
Therapeutic Group:
Neurology / Gynecology / Nutrition
Drug Category:
Active Folate Supplement (Vitamin B9 – Bioactive Form)
Content / Composition:
Each softgel contains:
* L-Methylfolate …… 600 mcg
Indications:
Indicated for folate supplementation and metabolic support, including:
* Folate deficiency
* Elevated homocysteine levels
* Prenatal and maternal health support
* Neural tube defect (NTD) prevention in pregnancy
* Cognitive function and mood support
* Adjunct in depression management (as methylfolate support)
Dosage:
As directed by the physician.
Typical regimen:
* 1 softgel daily
* Higher doses may be prescribed based on clinical need
Contraindications:
* Hypersensitivity to L-methylfolate
* Use caution in patients with vitamin B12 deficiency (masking effect)
Administration:
For oral use.
Take with water, with or without food.
Preferably at the same time each day.
Interaction:
Use caution with:
* Antiepileptic drugs (may alter folate metabolism)
* Methotrexate (folate pathway interaction)
* Antidepressants (used as adjunct therapy)
Compatibility:
Compatible with prenatal vitamins and multivitamin regimens.
Can be used alongside iron, calcium, and omega-3 supplements.
Stability / Storage:
Store below 25°C.
Protect from heat, moisture, and direct sunlight.
Keep out of reach of children.
Precautions:
* Monitor vitamin B12 levels in long-term use
* Use under medical supervision in pregnancy
* Do not exceed recommended dose unless prescribed
* Caution in patients with neurological disorders
Side Effects:
Generally well tolerated.
Possible mild effects:
* Nausea
* Bloating
* Sleep disturbances (rare)
Rare:
* Allergic reactions
* Irritability (high doses)
Website Note (Professional):
L-Methylfolate is the biologically active form of folate, offering superior bioavailability compared to folic acid.
Recommended under medical supervision for optimal therapeutic outcomes.
SYGFOL® Softgels
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