METRO-H® Tablets

METRO-H® Tablets
Generic Name:
Metronidazole
Therapeutic Group:
Anti-infective / Antiprotozoal
Drug Category:
Nitroimidazole Antibiotic
Content / Composition:
Each film-coated tablet contains:
* Metronidazole …… 500 mg
Indications:
Indicated for the treatment of:
* Amoebiasis (intestinal & hepatic)
* Giardiasis
* Trichomoniasis
* Bacterial vaginosis
* Anaerobic bacterial infections
* Dental infections (anaerobic origin)
* Intra-abdominal infections
Dosage:
As directed by the physician.
Typical dosing:
* Amoebiasis: 500–750 mg three times daily for 5–10 days
* Giardiasis: 250–500 mg twice to three times daily for 5–7 days
* Bacterial vaginosis: 500 mg twice daily for 7 days
* Anaerobic infections: 500 mg every 8 hours
Contraindications:
* Hypersensitivity to metronidazole or other nitroimidazoles
* First trimester of pregnancy (unless essential)
* Concomitant alcohol use (risk of disulfiram-like reaction)
Administration:
For oral use.
* Take with food to reduce gastric irritation
* Swallow with a full glass of water
* Complete full course of therapy
Interaction:
Use caution with:
* Alcohol (strictly avoid during and 48 hours after therapy)
* Warfarin (↑ anticoagulant effect)
* Lithium (↑ toxicity risk)
* Phenytoin & Phenobarbital
* Disulfiram
Compatibility:
Compatible with most antimicrobial regimens
Often used in combination therapy (e.g., H. pylori regimens)
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
* Avoid alcohol during treatment
* Use cautiously in hepatic impairment
* Prolonged use may cause peripheral neuropathy
* Monitor blood counts in long-term therapy
* Use with caution in neurological disorders
Side Effects:
Common:
* Nausea
* Metallic taste
* Abdominal discomfort
* Headache
Less common:
* Dizziness
* Vomiting
* Diarrhea
Rare but serious:
* Peripheral neuropathy
* Seizures
* Severe hypersensitivity reactions
Website Note (Professional):
Metronidazole is a well-established antimicrobial agent effective against anaerobic bacteria and protozoa, widely used in gastrointestinal, gynecological, and dental infections.