DOXYNUS® Capsules

DOXYNUS® Capsules
Generic Name:
Doxycycline
Therapeutic Group:
Anti-infective
Drug Category:
Tetracycline Antibiotic
Content / Composition:
Each capsule contains:
* Doxycycline …… 100 mg (or as per strength)
Indications:
Indicated for the treatment of:
* Respiratory tract infections
* Urinary tract infections
* Skin and soft tissue infections (including acne)
* Sexually transmitted infections (e.g., Chlamydia)
* Gastrointestinal infections
* Rickettsial infections
* Malaria prophylaxis (in endemic areas)
Dosage:
As directed by the physician.
Typical dosing:
* Initial: 100 mg twice daily on first day
* Maintenance: 100 mg once or twice daily depending on infection
* Duration: Based on severity and type of infection
Contraindications:
* Hypersensitivity to doxycycline or other tetracyclines
* Pregnancy and breastfeeding
* Children under 8 years (risk of tooth discoloration)
Administration:
For oral use.
* Take with a full glass of water
* Preferably take after food to reduce gastric irritation
* Do not lie down immediately after taking (to avoid esophageal irritation)
Interaction:
Use caution with:
* Antacids (calcium, magnesium, aluminum) – reduce absorption
* Iron supplements
* Oral contraceptives (reduced effectiveness)
* Warfarin (↑ anticoagulant effect)
* Barbiturates & anticonvulsants
Compatibility:
Compatible with most antibacterial regimens
Avoid co-administration with substances that impair absorption (e.g., dairy, antacids)
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
* Avoid excessive sunlight (photosensitivity risk)
* Use cautiously in hepatic impairment
* Long-term use may lead to superinfection
* Maintain adequate hydration
* Monitor for gastrointestinal irritation
Side Effects:
Common:
* Nausea
* Vomiting
* Diarrhea
* Photosensitivity
Less common:
* Esophagitis
* Skin rash
Rare but serious:
* Hepatotoxicity
* Severe allergic reactions
* Intracranial hypertension (very rare)
Website Note (Professional):
Doxycycline is a broad-spectrum tetracycline antibiotic widely used for treating a variety of infections with proven efficacy, convenient dosing, and excellent tissue penetration.