ETDOL-TH Tablets

ETDOL-TH Tablets
Generic Name:
Etoricoxib 90 mg + Thiocolchicoside 4 mg
Therapeutic Group:
Analgesic, Anti-inflammatory & Muscle Relaxant
Drug Category:
Selective COX-2 Inhibitor (NSAID) + Centrally Acting Muscle Relaxant
Content / Composition:
Each film-coated tablet contains:
Etoricoxib ………………… 90 mg
Thiocolchicoside ……… 4 mg
Excipients ………………… q.s.
Indications:
ETDOL-TH is indicated for:
Acute musculoskeletal pain
Low back pain (Lumbago)
Cervical and lumbar spondylosis
Muscle spasm associated with spine disorders
Sciatica
Post-traumatic muscle spasm
Orthopedic conditions with inflammation and stiffness
Dosage:
Adults: 1 tablet once daily or as directed by physician
Duration: Short-term use (usually 5–7 days)
Do not exceed recommended duration due to muscle relaxant safety profile
Contraindications:
Hypersensitivity to etoricoxib, thiocolchicoside, or NSAIDs
Active peptic ulcer or GI bleeding
Severe hepatic or renal impairment
Pregnancy and lactation
Women of childbearing potential not using contraception (thiocolchicoside warning)
Neuromuscular disorders (e.g., epilepsy risk)
Administration:
Oral use, preferably after food
Swallow with sufficient water
Avoid alcohol during treatment
Use strictly under medical supervision
Drug Interactions:
Anticoagulants → Increased bleeding risk
CNS depressants → Increased sedation
Other NSAIDs → Increased GI toxicity
Antihypertensives → Reduced effect
Drugs lowering seizure threshold → Increased risk (thiocolchicoside)
Compatibility:
Ideal for patients with pain + muscle spasm combination
Suitable for orthopedic and neurological pain conditions
Can be combined with physiotherapy for better outcomes
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
Use for short duration only (important for thiocolchicoside safety)
Monitor liver and kidney function
Use cautiously in elderly patients
Avoid prolonged use due to cardiovascular risk (etoricoxib)
Not recommended in chronic long-term therapy
Side Effects:
Common:
Dizziness
Drowsiness
Nausea
Gastric discomfort
Uncommon:
Diarrhea
Edema
Increased blood pressure
Serious (Rare):
Seizures (thiocolchicoside-related)
GI bleeding
Cardiovascular events
Hepatic dysfunction
Clinical Note:
ETDOL-TH provides a dual-action approach by combining:
Etoricoxib → potent anti-inflammatory & pain relief
Thiocolchicoside → effective muscle relaxation
This combination is highly effective for acute painful muscle spasm conditions, delivering fast relief, improved mobility, and reduced stiffness.