ETDOL-P Tablets

ETDOL-P Tablets
Generic Name:
Etoricoxib 60 mg + Paracetamol 325 mg
Therapeutic Group:
Analgesic & Anti-inflammatory
Drug Category:
Selective COX-2 Inhibitor (NSAID) + Non-Opioid Analgesic
Content / Composition:
Each film-coated tablet contains:
Etoricoxib ………………… 60 mg
Paracetamol …………… 325 mg
Excipients ………………… q.s.
Indications:
ETDOL-P is indicated for:
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis
Acute musculoskeletal pain
Dental pain
Post-operative pain
Dysmenorrhea (menstrual pain)
Acute gouty arthritis (pain management)
Dosage:
Adults: 1 tablet once daily or as directed by physician
In acute pain: may be used short-term under supervision
Maximum duration: use lowest effective dose for shortest time
Contraindications:
Hypersensitivity to etoricoxib, paracetamol, or NSAIDs
Active peptic ulcer or gastrointestinal bleeding
Severe hepatic impairment
Severe renal impairment
Established cardiovascular disease (e.g., ischemic heart disease, stroke)
Uncontrolled hypertension
Pregnancy (especially 3rd trimester)
Administration:
Oral use, with or without food
Swallow whole with water
Do not exceed recommended dose
Avoid concurrent use with other NSAIDs
Drug Interactions:
Anticoagulants (e.g., warfarin) → Increased bleeding risk
ACE inhibitors / ARBs → Reduced renal function
Diuretics → Reduced efficacy, risk of kidney issues
Other NSAIDs → Increased GI risk
Hepatotoxic drugs → Increased liver risk (paracetamol)
Compatibility:
Suitable for inflammatory pain conditions
Can be combined with gastroprotective agents if needed
Effective for both pain and inflammation control
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
Increased cardiovascular risk with long-term use
Use cautiously in elderly patients
Monitor liver and kidney function
Avoid in patients with history of GI bleeding
Not for long-term uncontrolled use
Side Effects:
Common:
Headache
Dizziness
Nausea
Dyspepsia
Uncommon:
Edema
Hypertension
Abdominal pain
Serious (Rare):
Cardiovascular events (MI, stroke)
GI bleeding
Liver toxicity
Severe skin reactions
Clinical Note:
ETDOL-P combines the selective anti-inflammatory action of etoricoxib (COX-2 inhibitor) with the analgesic effect of paracetamol, providing fast, effective, and targeted pain relief with improved gastrointestinal tolerability compared to traditional NSAIDs.