ZUROXIM Tablets (Cefuroxime + Clavulanic Acid)

ZUROXIM Tablets (Cefuroxime + Clavulanic Acid)
Generic Name:
Cefuroxime Axetil + Clavulanic Acid Tablets
Strength:
Cefuroxime 250 mg + Clavulanic Acid 125 mg
Therapeutic Group:
Antibacterial
Drug Category:
Second-Generation Cephalosporin + Beta-Lactamase Inhibitor
Content / Composition:
Each film-coated tablet contains:
Cefuroxime Axetil …………… 250 mg
Clavulanic Acid ……………… 125 mg
Excipients …………………… q.s.
Indications:
ZUROXIM is indicated for the treatment of susceptible bacterial infections including:
Upper respiratory tract infections (sinusitis, pharyngitis, tonsillitis)
Lower respiratory tract infections (bronchitis, pneumonia)
Urinary tract infections (UTIs)
Skin and soft tissue infections
Ear infections (otitis media)
Dental infections
Infections caused by beta-lactamase producing organisms
Dosage:
Adults & Adolescents:
1 tablet twice daily (every 12 hours)
Severe infections:
Dose may be adjusted as per physician
Duration:
Usually 5–10 days depending on infection
Contraindications:
Hypersensitivity to cephalosporins or beta-lactam antibiotics
History of severe allergic reaction to penicillins
Severe hepatic dysfunction related to clavulanate use
Administration:
Oral use only
Take after food for better absorption
Swallow whole with water
Complete full prescribed course
Drug Interactions:
Probenecid → increases cefuroxime levels
Anticoagulants → increased bleeding risk
Oral contraceptives → reduced effectiveness
Nephrotoxic drugs → caution
Compatibility / Clinical Benefits:
Broad-spectrum antibacterial activity
Effective against beta-lactamase producing bacteria
Enhanced efficacy in resistant infections
Suitable for respiratory & mixed infections
Reliable oral alternative to injectable therapy
Stability / Storage:
Store below 25°C
Protect from moisture and light
Keep in original packaging
Precautions:
Use with caution in renal impairment
Monitor liver function in prolonged use
Risk of antibiotic-associated colitis
Avoid unnecessary prolonged therapy
Side Effects:
Common:
Diarrhea
Nausea
Abdominal discomfort
Uncommon:
Headache
Skin rash
Elevated liver enzymes
Serious (Rare):
Hypersensitivity reactions
Stevens-Johnson syndrome
Hepatic dysfunction
Clinical Advantage:
ZUROXIM provides:
Dual mechanism (Antibiotic + Enzyme inhibitor)
Stronger action against resistant bacteria
Improved treatment outcomes in mixed infections
Excellent choice for respiratory & ENT infections
Packaging:
6 × 2 Tablets (Blister Pack)
Film-Coated Tablets