SURVORID-H® Tablets (25 mg)

Generic Name:
Levosulpiride
Therapeutic Group:
Gastrointestinal Therapeutics
Drug Category:
Prokinetic Agent / Selective Dopamine D₂ Receptor Antagonist
Content / Composition:
Each tablet contains:
* Levosulpiride …… 25 mg
Indications:
Indicated for the treatment of:
* Functional dyspepsia
* Irritable Bowel Syndrome (IBS)
* Gastroesophageal Reflux Disease (GERD)
* Delayed gastric emptying (gastroparesis)
* Nausea and vomiting associated with GI disorders
Dosage:
As directed by the physician.
Typical dose:
* 25 mg, 2–3 times daily before meals
* Dose may be adjusted based on clinical response
Contraindications:
* Hypersensitivity to levosulpiride
* Gastrointestinal bleeding, obstruction, or perforation
* Pheochromocytoma
* Epilepsy or seizure disorders
* Prolactin-dependent tumors (e.g., prolactinoma)
Administration:
* Oral administration
* Preferably taken before meals
* Swallow with sufficient water
* Follow physician’s instructions
Interaction:
* CNS depressants → increased sedation
* Antihypertensives → additive hypotensive effect
* Dopaminergic drugs (e.g., levodopa) → antagonistic effect
* Alcohol → enhances CNS side effects
Compatibility:
* Compatible with PPIs, antacids, and most GI therapies
* Avoid unnecessary combination with CNS depressants
Stability / Storage:
* Store below 25°C
* Protect from light and moisture
* Keep out of reach of children
Precautions:
* Use with caution in renal impairment (dose adjustment may be required)
* Monitor for extrapyramidal symptoms
* Risk of hyperprolactinemia with prolonged use
* Use cautiously in elderly patients
* Avoid long-term use without medical supervision
Side Effects:
Common:
* Drowsiness
* Fatigue
* Dizziness
Less common:
* Headache
* Gastrointestinal disturbances
Rare but serious:
* Extrapyramidal symptoms (tremor, rigidity)
* Hyperprolactinemia (galactorrhea, gynecomastia)
* Menstrual disturbances
Professional Note (For Website):
Levosulpiride is a highly selective dopamine D₂ receptor antagonist with dual prokinetic and anti-dyspeptic effects. It enhances gastrointestinal motility and modulates the gut–brain axis, making it an effective therapy for functional gastrointestinal disorders at lower and well-tolerated doses such as 25 mg