SUBMOX 1 g Tablets (Amoxicillin 1000 mg)

SUBMOX 1 g Tablets
(Amoxicillin 1000 mg)
Generic Name:
Amoxicillin
Therapeutic Group:
Antibacterial
Drug Category:
Aminopenicillin (Beta-Lactam Antibiotic)
Content / Composition:
Each film-coated tablet contains:
Amoxicillin (as Amoxicillin Trihydrate) ……… 1000 mg
Excipients ………………………………………… q.s.
Indications:
SUBMOX is indicated for the treatment of susceptible bacterial infections including:
Upper respiratory tract infections (pharyngitis, tonsillitis, sinusitis)
Lower respiratory infections (bronchitis, pneumonia)
Urinary tract infections (UTIs)
Skin and soft tissue infections
Ear infections (otitis media)
Dental infections
Gastrointestinal infections (including H. pylori as part of combination therapy)
Dosage:
Adults:
500 mg to 1000 mg every 8–12 hours depending on severity
Severe infections:
Higher doses may be required under physician supervision
Duration:
Typically 5–10 days
Contraindications:
Hypersensitivity to penicillins or beta-lactam antibiotics
History of severe allergic reactions (e.g., anaphylaxis)
Infectious mononucleosis (risk of rash)
Administration:
Oral use
Can be taken with or without food
Swallow with a full glass of water
Complete full course to prevent resistance
Drug Interactions:
Probenecid → increases amoxicillin levels
Oral contraceptives → reduced effectiveness
Allopurinol → increased risk of rash
Anticoagulants → monitor INR
Compatibility / Clinical Benefits:
Broad-spectrum antibacterial coverage
Effective against Gram-positive and some Gram-negative bacteria
Well tolerated and widely used first-line antibiotic
Suitable for community-acquired infections
Flexible dosing options
Stability / Storage:
Store below 25°C
Protect from moisture and light
Keep in original packaging
Precautions:
Use with caution in renal impairment (dose adjustment required)
Monitor for allergic reactions
Prolonged use may lead to superinfection
Use only for confirmed bacterial infections
Side Effects:
Common:
Nausea
Diarrhea
Skin rash
Uncommon:
Vomiting
Abdominal discomfort
Serious (Rare):
Anaphylaxis
Stevens-Johnson Syndrome
Antibiotic-associated colitis
Clinical Advantages:
SUBMOX 1 g provides:
High-dose rapid antibacterial action
Reliable first-line therapy
Effective in respiratory & ENT infections
Flexible use in combination therapies (e.g., H. pylori)
Packaging:
1 × 12 Tablets (Blister Pack)
Film-Coated Tablets