S-MOXY® Tablets

S-MOXY® Tablets
Generic Name:
Moxifloxacin
Therapeutic Group:
Anti-infective
Drug Category:
Fluoroquinolone Antibiotic (Fourth Generation)
Content / Composition:
Each film-coated tablet contains:
* Moxifloxacin Hydrochloride …… equivalent to Moxifloxacin 400 mg
Indications:
Indicated for the treatment of:
* Community-acquired pneumonia (CAP)
* Acute bacterial sinusitis
* Acute exacerbation of chronic bronchitis
* Complicated and uncomplicated skin & soft tissue infections
* Intra-abdominal infections (in combination therapy where required)
* Urinary tract infections (selected cases)
Dosage:
As directed by the physician.
Typical dosing:
* 400 mg once daily
* Duration: usually 5–14 days depending on infection type and severity
Contraindications:
* Hypersensitivity to moxifloxacin or other quinolones
* History of tendon disorders related to fluoroquinolones
* Known QT prolongation or cardiac arrhythmias
* Severe hepatic impairment
* Pregnancy and lactation
* Pediatric population
Administration:
For oral use.
* Take once daily, with or without food
* Swallow whole with sufficient water
* Avoid simultaneous intake with antacids, iron, or zinc preparations
Interaction:
* Antacids (Al/Mg), iron, zinc → reduce absorption
* QT-prolonging drugs (antiarrhythmics, macrolides) → increased cardiac risk
* Corticosteroids → increased risk of tendon rupture
* Warfarin → monitor coagulation parameters
* NSAIDs → potential CNS stimulation
Compatibility:
Compatible with most antibacterial regimens
Avoid co-administration with drugs affecting QT interval or absorption
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
* Risk of QT interval prolongation (monitor cardiac patients)
* Tendonitis and tendon rupture risk (especially elderly)
* Use cautiously in hepatic impairment
* Avoid excessive sunlight exposure (photosensitivity)
* Monitor for CNS effects (dizziness, confusion)
* Discontinue if severe diarrhea occurs
Side Effects:
Common:
* Nausea
* Diarrhea
* Headache
* Dizziness
Less common:
* Abdominal pain
* Insomnia
* Mild liver enzyme elevation
Serious (rare):
* QT prolongation
* Tendon rupture
* Severe hypersensitivity reactions
* Hepatotoxicity
* Peripheral neuropathy
Professional Web Note:
Moxifloxacin is a fourth-generation fluoroquinolone offering enhanced activity against Gram-positive, Gram-negative, and atypical pathogens, with excellent tissue penetration and once-daily dosing for improved patient compliance.