FLAVIDO™ Tablets

FLAVIDO™ Tablets
Generic Name:
Cinnarizine 20 mg + Domperidone 15 mg
Therapeutic Group:
Anti-Vertigo & Antiemetic Agents
Drug Category:
Calcium Channel Blocker (Cinnarizine) + Dopamine Antagonist (Domperidone)
Content / Composition:
Each tablet contains:
Cinnarizine …………………………… 20 mg
Domperidone ………………………… 15 mg
Excipients ……………………………… q.s.
Indications:
FLAVIDO is indicated for:
Vertigo (vestibular disorders)
Nausea and vomiting
Motion sickness
Ménière’s disease
Balance disorders
Gastrointestinal-related nausea
Dosage:
Adults: 1 tablet 2–3 times daily
Preferably taken before meals
Dose may be adjusted based on severity
For motion sickness: take 1 tablet 1–2 hours before travel
As directed by the physician
Contraindications:
Hypersensitivity to cinnarizine or domperidone
Prolactin-secreting tumors (prolactinoma)
Severe hepatic impairment
Gastrointestinal obstruction or bleeding
Known cardiac arrhythmias or prolonged QT interval
Concomitant use with strong CYP3A4 inhibitors
Administration:
Oral use with water
Best taken before meals
Do not exceed recommended dose
Drug Interactions:
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) → Increased domperidone levels
CNS depressants → Enhanced sedative effect
Anticholinergics → May reduce effect of cinnarizine
QT-prolonging drugs → Increased cardiac risk
Compatibility:
Can be used with anti-vertigo and antiemetic therapies
Suitable for short-term and symptomatic management
Dual-action provides central and peripheral symptom control
Stability / Storage:
Store below 25°C
Protect from moisture and light
Keep out of reach of children
Precautions:
Use cautiously in elderly patients
May cause drowsiness — avoid driving or operating machinery
Monitor cardiac patients carefully
Avoid long-term use without medical supervision
Use cautiously in Parkinson’s disease (cinnarizine effect)
Side Effects:
Common:
Drowsiness
Dry mouth
Fatigue
Gastrointestinal discomfort
Uncommon:
Weight gain
Headache
Dizziness
Serious (Rare):
Extrapyramidal symptoms
Cardiac arrhythmias (QT prolongation)
Hyperprolactinemia (domperidone-related)
Clinical Note:
FLAVIDO™ offers a dual-action mechanism combining vestibular suppression (cinnarizine) and antiemetic activity (domperidone), making it highly effective for managing vertigo, motion sickness, and nausea with rapid symptomatic relief.