CEFNUS Pediatric Suspension

CEFNUS Pediatric Suspension
(Cefixime 100 mg/5 mL)
Generic Name:
Cefixime
Therapeutic Group:
Antibacterial
Drug Category:
Third-Generation Cephalosporin Antibiotic
Content / Composition:
After reconstitution, each 5 mL contains:
Cefixime ………………………………… 100 mg
Excipients (including flavoring agents) … q.s.
Indications:
CEFNUS 100 mg/5 mL Suspension is indicated for pediatric use in:
Upper respiratory tract infections (pharyngitis, tonsillitis, sinusitis)
Lower respiratory infections (bronchitis, pneumonia)
Otitis media
Urinary tract infections (UTIs)
Typhoid fever
Gastrointestinal bacterial infections
Dosage:
Children (≥ 6 months):
8 mg/kg/day as a single daily dose
یا
4 mg/kg every 12 hours
Maximum Dose:
400 mg/day
Typical Duration:
5–10 days
Typhoid: 7–14 days (as directed by physician)
Contraindications:
Hypersensitivity to cefixime or cephalosporins
Severe allergy to penicillins (cross-reactivity risk)
Administration:
For oral use only
Reconstitute with clean water to marked level
Shake well before each use
Measure dose using syringe or cup
Can be taken with or without food
Drug Interactions:
Anticoagulants → increased bleeding risk
Carbamazepine → increased plasma levels
Probenecid → increases cefixime levels
Compatibility / Clinical Benefits:
مناسب برای کودکان (Pediatric-friendly)
Taste-enhanced formulation → better compliance
Once-daily dosing possible
Broad-spectrum antibacterial coverage
Effective in outpatient pediatric infections
Stability / Storage:
Store dry powder below 25°C
After reconstitution:
Use within 7–14 days
Keep tightly closed
Protect from light
Do not freeze
Precautions:
Use with caution in renal impairment
Monitor for hypersensitivity reactions
Risk of antibiotic-associated diarrhea
Avoid prolonged unnecessary use
Side Effects:
Common:
Diarrhea
Nausea
Abdominal pain
Uncommon:
Skin rash
Headache
Serious (Rare):
Anaphylaxis
Stevens-Johnson Syndrome
Clostridium difficile-associated diarrhea
Clinical Advantages:
CEFNUS 100 mg/5 mL offers:
Accurate pediatric dosing (low-strength flexibility)
High safety profile in children
Improved palatability → better adherence
Reliable efficacy against common infections
Packaging:
30 mL bottle (after reconstitution)
Measuring cup + oral syringe included