AZINUS 500 Tablets

AZINUS 500 Tablets
Generic Name:
Azithromycin 500 mg
Therapeutic Group:
Antibacterial (Antibiotic)
Drug Category:
Macrolide Antibiotic (Azalide Class)
Content / Composition:
Each film-coated tablet contains:
Azithromycin ………………… 500 mg
Excipients …………………… q.s.
Indications:
AZINUS 500 is indicated for the treatment of infections caused by susceptible microorganisms, including:
Upper respiratory tract infections (sinusitis, pharyngitis, tonsillitis)
Lower respiratory tract infections (bronchitis, pneumonia)
Ear infections (otitis media)
Skin and soft tissue infections
Sexually transmitted infections (e.g., uncomplicated chlamydia)
Dental infections
Dosage:
Adults:
500 mg once daily for 3 days
or
500 mg on Day 1, followed by 250 mg once daily for 4 days
STIs (e.g., Chlamydia):
Single dose of 1 g (as directed by physician)
Note: Follow physician’s prescription based on infection type
Contraindications:
Hypersensitivity to azithromycin or other macrolide antibiotics
Severe hepatic impairment
History of cholestatic jaundice/hepatic dysfunction associated with azithromycin
Administration:
Oral use, with or without food
Take once daily
Avoid antacids containing aluminum/magnesium within 2 hours
Complete full course even if symptoms improve
Drug Interactions:
Antacids → Reduced absorption
Warfarin → Increased bleeding risk
Digoxin → Increased levels
QT-prolonging drugs → Risk of arrhythmia
Ergot derivatives → Contraindicated
Compatibility:
Effective against Gram-positive, Gram-negative & atypical bacteria
Suitable for community-acquired infections
Convenient once-daily dosing improves compliance
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
Use cautiously in patients with liver disease
Risk of QT prolongation (cardiac patients)
Avoid unnecessary use to prevent antibiotic resistance
Not effective for viral infections
Use carefully in elderly patients
Side Effects:
Common:
Nausea
Diarrhea
Abdominal pain
Uncommon:
Headache
Dizziness
Rash
Serious (Rare):
Hepatotoxicity
QT prolongation / arrhythmias
Severe allergic reactions (anaphylaxis)
Clinical Note:
AZINUS 500 (Azithromycin) is a broad-spectrum macrolide antibiotic with:
Once-daily dosing
Excellent tissue penetration
Prolonged half-life
It provides effective and convenient treatment for a wide range of bacterial infections, improving patient compliance and clinical outcomes.