LEEVOXY® 500 Tablets

LEEVOXY® 500 Tablets
Generic Name:
Levofloxacin
Therapeutic Group:
Anti-infective
Drug Category:
Fluoroquinolone Antibiotic (Third Generation)
Content / Composition:
Each film-coated tablet contains:
* Levofloxacin …… 500 mg
Indications:
Indicated for the treatment of:
* Community-acquired pneumonia (CAP)
* Acute bacterial sinusitis
* Acute exacerbation of chronic bronchitis
* Urinary tract infections (UTIs)
* Complicated urinary infections & pyelonephritis
* Skin and soft tissue infections
* Prostatitis
Dosage:
As directed by the physician.
Typical dosing:
* 500 mg once daily
* Duration: usually 5–14 days depending on infection severity
Contraindications:
* Hypersensitivity to levofloxacin or other fluoroquinolones
* History of tendon disorders associated with quinolones
* Epilepsy or seizure disorders
* Pregnancy and lactation
* Pediatric patients
Administration:
For oral use.
* Take once daily with or without food
* Swallow with adequate water
* Avoid co-administration with antacids, calcium, iron, or zinc
Interaction:
* Antacids (Al/Mg), iron, calcium → decrease absorption
* Warfarin → increased bleeding risk (monitor INR)
* NSAIDs → increased CNS stimulation risk
* Corticosteroids → increased tendon rupture risk
* QT-prolonging drugs → increased cardiac risk
Compatibility:
Compatible with most antibacterial therapies
Avoid simultaneous intake with absorption-reducing agents
Stability / Storage:
Store below 25°C
Protect from light and moisture
Keep out of reach of children
Precautions:
* Risk of tendonitis and tendon rupture (especially elderly patients)
* Dose adjustment required in renal impairment
* Avoid prolonged sun exposure (photosensitivity)
* Monitor CNS effects (dizziness, confusion)
* Risk of QT prolongation in predisposed patients
* Discontinue if severe diarrhea occurs
Side Effects:
Common:
* Nausea
* Diarrhea
* Headache
* Dizziness
Less common:
* Insomnia
* Skin rash
* Elevated liver enzymes
Serious (rare):
* Tendon rupture
* QT prolongation
* Severe hypersensitivity reactions
* Peripheral neuropathy
* Hepatotoxicity
Professional Web Note:
Levofloxacin is a highly effective broad-spectrum fluoroquinolone antibiotic with excellent bioavailability, strong activity against respiratory and urinary pathogens, and convenient once-daily dosing for improved patient compliance.