BACLOF-H Tablets

BACLOF-H Tablets
Generic Name:
Baclofen 10 mg
Therapeutic Group:
Skeletal Muscle Relaxants
Drug Category:
GABA-B Receptor Agonist (Centrally Acting Muscle Relaxant)
Content / Composition:
Each tablet contains:
Baclofen ……………………………… 10 mg
Excipients …………………………… q.s.
Indications:
BACLOF-H is indicated for:
Muscle spasticity of spinal origin
Multiple sclerosis–related spasticity
Spinal cord injuries
Cerebral palsy
Muscle stiffness and spasms
Neuromuscular disorders
Dosage:
Initial dose: 5 mg three times daily
Gradually increase every 3–7 days based on response
Usual maintenance dose: 30–80 mg per day in divided doses
Maximum dose: As per physician recommendation
Do not discontinue abruptly
As directed by the physician
Contraindications:
Hypersensitivity to baclofen
History of severe renal impairment (without dose adjustment)
Use cautiously in epilepsy patients
Peptic ulcer disease (with caution)
Administration:
Oral use with or after food
Swallow with water
Gradual dose titration required
Gradual withdrawal recommended to avoid withdrawal symptoms
Drug Interactions:
CNS depressants (e.g., benzodiazepines, alcohol) → Increased sedation
Antihypertensives → Enhanced hypotensive effect
Antidepressants → May enhance CNS depression
Levodopa → Risk of hallucinations and confusion
Compatibility:
Can be used with physiotherapy and rehabilitation programs
Suitable for long-term management under medical supervision
Effective in combination with other neuromuscular therapies
Stability / Storage:
Store below 25°C
Protect from moisture and light
Keep out of reach of children
Precautions:
Avoid sudden discontinuation (risk of withdrawal, seizures, hallucinations)
Use cautiously in renal impairment
May cause sedation — avoid driving or machinery
Monitor elderly patients closely
Use cautiously in psychiatric disorders
Side Effects:
Common:
Drowsiness
Dizziness
Weakness
Fatigue
Uncommon:
Hypotension
Confusion
Nausea
Serious (Rare):
Respiratory depression
Seizures (withdrawal-related)
Hallucinations
Bradycardia
Clinical Note:
BACLOF-H (Baclofen) acts centrally on GABA-B receptors to reduce muscle spasticity and improve mobility. It is widely used in neurological conditions requiring long-term spasm control and neuromuscular stabilization.