CEFNUS 400 mg Capsules

CEFNUS 400 mg Capsules
(Cefixime 400 mg)
Generic Name:
Cefixime
Therapeutic Group:
Antibacterial
Drug Category:
Third-Generation Cephalosporin Antibiotic
Content / Composition:
Each capsule contains:
Cefixime ………………………………… 400 mg
Excipients ……………………………… q.s.
Indications:
CEFNUS 400 mg is indicated for the treatment of moderate to severe bacterial infections including:
Upper respiratory tract infections (pharyngitis, tonsillitis, sinusitis)
Lower respiratory infections (acute & chronic bronchitis)
Urinary tract infections (UTIs)
Ear infections (otitis media)
Typhoid fever
Uncomplicated gonorrhea
Gastrointestinal infections
Dosage:
Adults & Adolescents:
400 mg once daily
یا
200 mg twice daily
Duration:
Typically 5–10 days
Typhoid fever: 7–14 days (as per physician)
Contraindications:
Hypersensitivity to cephalosporins or beta-lactam antibiotics
History of severe allergic reactions
Administration:
Oral use
Can be taken with or without food
Swallow capsule with water
Complete full prescribed course
Drug Interactions:
Anticoagulants → increased bleeding risk
Carbamazepine → increased plasma levels
Probenecid → may increase cefixime concentration
Compatibility / Clinical Benefits:
Broad-spectrum antibacterial activity
Strong efficacy against Gram-negative pathogens
High resistance to beta-lactamase enzymes
Convenient once-daily dosing
Ideal for outpatient and step-down therapy
Stability / Storage:
Store below 25°C
Protect from moisture and light
Keep in original packaging
Precautions:
Use with caution in renal impairment
Monitor for allergic reactions
Risk of antibiotic-associated diarrhea/colitis
Avoid prolonged or unnecessary use
Side Effects:
Common:
Diarrhea
Nausea
Abdominal pain
Uncommon:
Headache
Dizziness
Skin rash
Serious (Rare):
Hypersensitivity reactions
Stevens-Johnson Syndrome
Severe colitis (C. difficile)
Clinical Advantages:
CEFNUS 400 mg provides:
High-strength third-generation antibiotic therapy
Convenient once-daily dosing improves compliance
Effective against resistant and complicated infections
Strong choice for respiratory & systemic infections
Packaging:
1 × 5 Capsules (Blister Pack)