VELO-H DS® Oral Suspension 250 mg/5 mL
Cefradine Oral Suspension BP (Double Strength)
Generic Name:
Cefradine
Therapeutic Group:
Antibacterial (Cephalosporin – 1st Generation)
Drug Category:
Broad-Spectrum Antibiotic (Pediatric Double Strength Suspension)
Content / Composition:
Each 5 mL reconstituted suspension contains:
* Cefradine BP …… 250 mg
* Flavoured base (Orange)
* Excipients …… q.s.
Indications:
* Respiratory tract infections (pharyngitis, tonsillitis, bronchitis)
* Urinary tract infections (UTIs)
* Skin & soft tissue infections
* Ear infections (otitis media)
* Moderate to severe pediatric bacterial infections
Dosage:
As directed by the physician
Children:
* 25–50 mg/kg/day in divided doses (every 6–12 hours)
Severe infections:
* Up to 75–100 mg/kg/day
Advantage of DS:
✔️ Lower volume per dose
✔️ Better compliance in children
Contraindications:
* Hypersensitivity to cephalosporins
* Severe penicillin allergy (cross-reactivity risk)
Administration:
* Oral use
* Shake well before use
* Measure accurately using dosing cup/spoon
* Can be taken with or without food
Interaction:
* Probenecid ↑ Cefradine concentration
* Anticoagulants ↑ bleeding tendency
* Aminoglycosides ↑ nephrotoxicity
* Loop diuretics ↑ renal risk
Compatibility:
* Compatible with routine pediatric therapies
* Avoid concurrent use with nephrotoxic agents when possible
Stability / Storage:
* Dry powder: Store below 25°C
* After reconstitution:
✔️ Use within 7–10 days
✔️ Store in refrigerator (2–8°C)
* Protect from light
Precautions:
* Use cautiously in renal impairment
* Monitor for hypersensitivity reactions
* Prolonged use may lead to superinfection
* Ensure full course completion to avoid resistance
Side Effects:
Common:
* Diarrhea
* Nausea
* Abdominal discomfort
Less Common:
* Skin rash
* Vomiting
Serious (Rare):
* Anaphylaxis
* Severe colitis (C. difficile)
* Blood dyscrasias
Professional Summary:
VELO-H DS® 250 mg/5 mL is a high-strength pediatric cephalosporin suspension offering:
✔️ Strong antibacterial coverage
✔️ Reduced dosing volume (child-friendly)
✔️ Enhanced compliance in moderate to severe infections
Ideal for pediatric respiratory, urinary, ENT, and systemic infections requiring higher dosing strength.
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