ESO-H® 40 mg Capsules
Esomeprazole – Delayed-Release (Enteric-Coated)
Generic Name:
Esomeprazole
Therapeutic Group:
Gastrointestinal Agents
Drug Category:
Proton Pump Inhibitor (PPI) / Antiulcer
Content / Composition:
Each delayed-release capsule contains:
* Esomeprazole …… 40 mg
* Enteric-coated pellets (acid-resistant)
* Excipients …… q.s.
Indications:
* Gastroesophageal Reflux Disease (GERD)
* Severe or chronic heartburn
* Erosive esophagitis (healing & maintenance)
* Gastric & duodenal ulcers
* NSAID-associated ulcers
* Zollinger–Ellison syndrome
* H. pylori eradication (in combination therapy)
Dosage:
As directed by the physician
Adults:
* 20–40 mg once daily (standard therapy)
* Severe GERD: 40 mg daily for 4–8 weeks
H. pylori therapy:
* In combination with antibiotics (triple therapy regimen)
Contraindications:
* Hypersensitivity to esomeprazole or other PPIs
* Concomitant use with nelfinavir
Administration:
* Oral use
* Take before meals (preferably morning)
* Swallow whole; do not crush or chew
* Capsule may be opened and pellets mixed with water if needed
Interaction:
May interact with:
* Clopidogrel (reduced effect)
* Warfarin (monitor INR)
* Diazepam
* Phenytoin
May reduce absorption of:
* Ketoconazole
* Iron salts
Compatibility:
* Compatible with antibiotics (H. pylori regimen)
* Can be used with antacids (short-term relief)
Stability / Storage:
* Store below 25°C
* Protect from moisture & light
* Keep in original packaging
Precautions:
* Long-term use may cause:
Vitamin B12 deficiency
Hypomagnesemia
* Increased risk of fractures (long-term use)
* Rule out gastric malignancy before therapy
* Use with caution in hepatic impairment
Side Effects:
Common:
* Headache
* Abdominal pain
* Diarrhea
* Nausea
Less Common:
* Constipation
* Flatulence
Rare but Serious:
* Hypersensitivity reactions
* Electrolyte imbalance
* Clostridium difficile-associated diarrhea
Professional Summary:
ESO-H® (Esomeprazole) is a next-generation PPI offering:
✔️ Stronger and more consistent acid suppression than conventional PPIs
✔️ Rapid symptom relief in GERD and heartburn
✔️ Effective healing of erosive esophagitis
✔️ Once-daily convenient dosing
👉 Ideal for moderate to severe GERD patients
👉 Preferred choice for long-term acid control therapy
